Viewpoints
Producing Nano-particles for formulation: the alternative approach
Viewpoints - June 2010
Formulation issues might hamper the therapeutic possibilities of Active Pharmaceutical Ingredients and their commercial success.
Several traditional approaches have been developed to create nano-particles, with different degrees of success. Using Carbon Dioxide as an alternative for organic solvents typically used to make nano-particles opens a new world of possibilities.
Solvent free nano-particles can be processed further to achieve the optimal bio-availability profile.